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Beilstein J. Org. Chem. 2014, 10, 1383–1389, doi:10.3762/bjoc.10.141
Graphical Abstract
Figure 1: Biologically active agents containing a 3-substituted-3-aminooxindole core.
Figure 2: ORTEP [37] view of one of the two independent molecules of 4a present in the asymmetric unit, showing t...
Figure 3: Proposed explanation of the stereochemical outcome of the Ugi 3CR.
Scheme 1: Post-Ugi transformation on compound 10a.
Scheme 2: Post-Ugi cyclization on compound 15a.
Beilstein J. Org. Chem. 2013, 9, 147–154, doi:10.3762/bjoc.9.17
Figure 1: THBC-DKP-based natural and synthetically made compounds.
Figure 2: THBC-DKP-based peptidomimetic 1a.
Figure 3: Geometric parameters for mimics 1a,b.
Figure 4: Perspective view of the low-energy conformers of 1a,b. Hydrogen atoms are omitted for clarity.
Scheme 1: Synthesis of the THBC-DKP-based peptidomimetic 1a.